Providing greater certainty
in mole evaluation.

Orlucent^® has developed the first handheld fluorescent molecular imaging system to non-invasively evaluate early tissue remodeling that signals a mole’s transition to atypia.

Higher fluorescence indicates probable tissue remodeling

Reveals suspicious tissue remodeling invisible to the naked eye

The Orlucent system evaluates biological activity originating from within the mole

High biological activity

Low biological activity

High biological activity

Low biological activity

¹ Friedman et al. The “dysplastic” nevus

² Haenssle et al. Results of a surveillance programme for patients at high risk of malignant melanoma using digital and conventional dermoscopy

³ Annessi et al. Correlation between clinical atypia and histologic dysplasia in acquired melanocytic nevi

⁴ Elmore et al. Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study

⁵ March et al. Practical application of new technologies for melanoma diagnosis: Part I

⁶ Angelucci D. Diagnosis: Melanoma: What emerging tests and tech mean for dermatologists

⁷ Elmore et al. Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study

Current mole evaluation methods are visual and subjective

Tissue remodeling is indicative of a nevus transforming to atypia and atypical nevi have a potential to become melanoma.¹ Unfortunately, current visual assessment methods are not always sufficient to distinguish between benign or suspicious atypical moles.² ⁻ ⁴ For this reason, biopsy is often used to gain histopathological information. However, this takes time and biopsies have some risk of causing infection and scarring.

The Orlucent system is biologically based and objective